It is observed by over 50 charitable/support organizations based in over 40 countries around the world. Angelman syndrome (AS) affects one in 15,000 live births, or 500,000 people worldwide.

Awareness efforts, such a lighting architecture and buildings, in honor of International Angelman Day increases public knowledge of the conditions, builds inclusion and understanding, and most importantly spreads the message that the global collective of Angelman syndrome organizations is working tirelessly to bring practical treatments to Angelman syndrome as quickly as possible.